Actovegin 200 mg/5 ml. (5 ampoules)
- Manufacturer: Takeda (Japan)
- Product Code: acto200
- Availability: In Stock
44.00€
- Delivery within EU (3-5 days)
Actovegin 200 mg / 5 ml – 5 Ampoules
Actovegin 200 mg is an injectable preparation containing a deproteinized hemoderivative of calf blood. Each 5 ml ampoule contains 200 mg of the active substance calculated as dry weight. The product is supplied as a pack of 5 ampoules.
Actovegin has attracted particular interest in sports medicine because of research into cellular energy metabolism, mitochondrial function and skeletal muscle recovery.
Product Information
Why Actovegin Is Discussed in Sports Pharmacology
Interest in Actovegin among athletes and sports-medicine researchers is primarily related to its proposed effects on cellular energy metabolism rather than to a direct stimulant effect.
Experimental research has investigated several areas that may be relevant to intensive training:
- Mitochondrial oxidative metabolism
- Cellular oxygen utilization
- Glucose metabolism
- ATP-related energy production
- Skeletal muscle recovery
- Response to metabolic stress
Mitochondrial Function and Muscle Metabolism
One of the most interesting areas of Actovegin research concerns skeletal muscle mitochondria. Mitochondria are responsible for oxidative energy production and therefore play a central role in endurance, training adaptation and recovery.
A study using permeabilized human skeletal muscle fibers found that acute exposure to Actovegin increased mitochondrial oxidative phosphorylation capacity in a concentration-dependent manner. The researchers reported increased respiratory capacity involving mitochondrial Complex I and Complex I + II pathways.
Actovegin increases oxidative capacity in human skeletal muscle – European Journal of Sport Science →
Actovegin and Exercise Performance
The available human performance research is much less conclusive. A controlled study investigated intravenous Actovegin in physically active men during exhaustive exercise. Researchers measured peak power, oxygen consumption, blood lactate, glucose and several physiological performance parameters.
No effect of intravenous Actovegin on peak aerobic capacity – International Journal of Sports Medicine →
Recent Research: Actovegin and High-Intensity Training
A 2026 experimental study examined Actovegin alone and in combination with high-intensity interval training. The researchers investigated exercise capacity together with mitochondrial respiratory function.
Actovegin increased mitochondrial respiratory capacity, while the combination of Actovegin and high-intensity training produced a larger improvement in exercise performance than training alone.
Muscle Recovery and Sports Injuries
Actovegin has also been used historically in sports medicine in connection with muscle injuries. Small clinical studies and observational reports have investigated its possible role in reducing recovery time after muscle strains, including research involving football players.
Some reports have suggested faster return to play, but the available evidence is limited by small study populations and differences in treatment protocols.
Cellular Oxygen and Glucose Metabolism
Actovegin has been investigated for its effects on cellular oxygen and glucose metabolism. These pathways are particularly relevant to skeletal muscle because both glucose availability and mitochondrial oxygen utilization contribute to ATP production during physical activity.
Rather than functioning as a stimulant, Actovegin is generally discussed as a metabolic modulator. The proposed mechanisms concern cellular substrate utilization and mitochondrial energy production.
Actovegin 200 mg Composition
According to the official Austrian product information, one 5 ml ampoule contains:
- 200 mg deproteinized hemoderivative of calf blood, calculated as dry weight
- Water for injection
- Hydrochloric acid for pH adjustment
The solution is clear to slightly yellowish.
Route of Administration
Actovegin 200 mg / 5 ml is an injectable medicinal product. According to the Austrian Summary of Product Characteristics, this formulation is intended for intravenous administration. Administration of injectable medicines should be performed by an appropriately qualified healthcare professional and according to the approved product information applicable in the relevant country.
Research Summary
Current sports-related research suggests that Actovegin can influence mitochondrial metabolism in skeletal muscle, which provides a scientifically plausible reason for continued interest in the product among athletes and sports researchers.
For athletes, Actovegin is therefore best viewed as an experimentally studied metabolic preparation.
Scientific References
- Søndergård SD, Dela F, Helge JW, Larsen S. Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. European Journal of Sport Science. 2016.
PubMed: PMID 26744809 → - Lee P, Nokes L, Smith PM. No effect of intravenous Actovegin on peak aerobic capacity. International Journal of Sports Medicine. 2012.
PubMed: PMID 22318562 →
FAQ
Why is Actovegin used in sports-related contexts?
Interest is mainly connected with its effects on cellular metabolism, mitochondrial respiration, oxygen utilization and skeletal muscle recovery rather than with stimulant activity.
Does Actovegin increase endurance?
This has not been reliably demonstrated in humans. Experimental studies show effects on mitochondrial function.
Does Actovegin improve mitochondrial function?
Laboratory research using human skeletal muscle fibers has demonstrated increased mitochondrial oxidative capacity after exposure to Actovegin.
Has Actovegin been studied for muscle recovery?
Yes. Actovegin has appeared in sports-medicine research involving muscle injuries and return-to-play protocols. Some studies have reported potentially faster recovery, although the quality and quantity of evidence are limited.
Is Actovegin a stimulant?
No. Actovegin is generally studied as a metabolic preparation rather than as a central nervous system stimulant.
Delivery within the EU
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